Designing a New Global Scientific Assessment Body for Pandemics

 

The Pandemic Risk Outlook (PRO), a PAX sapiens initiative, drives political focus on pandemic risk and prevention, keeping them central to global discourse and decision-making. Amid ongoing pandemic reform efforts—including progress toward a WHO pandemic agreement—PAX has a forward-looking assessment agenda to unveil options for a scientific body with the capacity to assess, predict, detect, and help control future pandemics. This initiative is led by PAX sapiens Dr. Louise Gresham, Senior Fellow, Global Health Security. Linkedin 

Initiative Advisor

Louise Gresham

Louise Gresham Headshot

A Critical Window: A Publication About this Initiative

Pandemic Risk Outlook (PRO), a PAX sapiens initiative, advances the creation of a process that enables governments, scientific institutions, and non-state actors to jointly assess pandemic risk and direct financing to reduce it. PRO’s three-phase pathway—Validate, Design, Build—aims to ensure this process is scientifically rigorous, politically viable, and aligned with global priorities. Since the October 2024 Brazil pandemic risk assessment workshop co-hosted by the National Academy and FioCruz, PRO has deepened support on risk drivers and methodological foundations. A July 2025 convening co-hosted with IPPS and IPPPR linked scientific work to governance, followed by further momentum at the UNF–NAM Science Strategy meeting in November 2025 as the initiative enters its Build phase.

With UN deliberations, IHR amendments, and pandemic accord negotiations ahead in 2026, the coming year offers a narrow but critical window to institutionalize this capability and help redefine the global health architecture of pandemic risk. This anthology shows how PAX sapiens is helping sustain political will at a moment of historic opportunity – and historic risk.

Download A Critical Window here.
Publications

The Lancet
The Pandemic Agreement is a milestone: now it is time for action in national capitals
Clark, H., & Sirleaf Johnson, E. (2025, June)

National Academy of Medicine Perspective
The imperative of a global pandemic risk framework
Dzau, V. J., Oliveira Aguiar, M. de L., & Phumaphi, J. (2025, June)

Oxford University Pandemic Sciences Institute (abstract)
Pandemic Governance: Breaking the mismatch between planetary challenges and existing system capabilities
Gresham, L., Carlson, C., Oppenheim, B., Blake, J. (2025, July)

The Independent Panel for Pandemic Preparedness and Response
Advancing the global agenda for pandemic risk assessment: How could a multisectoral scientific synthesis inform pandemic risk priorities and investments? (2025, May)

The Independent Panel for Pandemic Preparedness and Response
Pandemic readiness in an uncertain world—a set of four policy briefs.
Clark, H., & Sirleaf Johnson, E. (2025, May)